2 edition of Studies on copper metabolism in the cotton rat Sigmondon hispidus texianus found in the catalog.
Studies on copper metabolism in the cotton rat Sigmondon hispidus texianus
David Bayard Milne
Written in English
|Statement||by David Bayard Milne.|
|The Physical Object|
|Pagination||49 leaves, bound :|
|Number of Pages||49|
Slade, N.A. and R.K. Swihart. Home range indices for the hispid cotton rat (Sigmodon hispidus) in northeastern Kansas. Journal of Mammalogy 64(4) Explore the latest questions and answers in Copper Metabolism, and find Copper Metabolism experts. Questions (2) Some studies show that copper can be used for controlling mosquito breeding.
1. Eighty-seven rats were fed a diet of milk treated with hydrogen sulphide together with copper-free mineral and vitamin supplements. Forty-three of the eighty-seven rats were used controls and given Cu supplements varying from 50 to μg/week. In addition to the eighty-seven rats, twenty-eight rats were fed a commercial diet. 2. ISBN: OCLC Number: Notes: "Proceedings of the American Chemical Society Symposium on Copper Bioavailability and Metabolism, held April , , in Dallas, Texas"--Title page verso.
Copper deficiency and copper overload have multiple and significant effects on systemic and cellular lipid metabolism. Recent studies indicate that copper misbalance is an emerging factor in dyslipidemia and/or fatty-liver disease. In turn, lipid metabolism could be an important modifier of the time-of-onset and severity in Wilson’s disease. Because defects in liver copper metabolism appear to be a critical factor in the pathogenesis of Wilson's disease and the hepatocarcinogenesis in LEC rats, and because of our earlier observation of low serum CP activity in DEHP-treated rats, we tested whether copper metabolism is altered in this PP model, which involves changes in metabolic.
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Studies on copper metabolism in the cotton rat Sigmondon hispidus texianus hemoglobin levels,\ud and cytochrome c oxidase activities were determined in the cotton\ud rat. The response of the cotton rat to different levels of copper was\ud analagous to that of the common laboratory rat.
The blood and liver\ud copper patterns followed a. Studies on copper metabolism in the cotton rat Sigmondon hispidus texianus Public Deposited.
and cytochrome c oxidase activities were determined in the cotton rat. The response of the cotton rat to different levels of copper was analagous to that of the common laboratory rat.
The blood and liver copper patterns followed a course similar Author: David Bayard Milne. Comp. Biochem. Physiol. Vol. 75A, No. 4, pp. toPrinted in Great Britain /+ Pergamon Press Ltd A COMPARISON OF THE WATER RELATIONS OF THE HISPID COTTON RAT, SIGMODON HISPIDUS, AND THE PRAIRIE VOLE, MICROTUS OCHROGASTER R.
KEITH DUPR Department of Zoology, Iowa State University, Ames, 1ACited by: 1. Don Wilson and Sue Ruff (), The Smithsonian Book of North American Mammals [ ] William Burt et al.
(), A Field Guide to Mammals [ ] Robel et al. (), Environmental, age, and sex effects on cotton rat (Sigmodon hispidus) hematology (PubMed). The resistance of cotton rats, Sigmodon hispidus to Nippostrongylus brasiliensis infection was examined and compared the response to that of the susceptible Indian soft-furred rat, Millardia a primary infection with infective third-stage N.
brasiliensis larvae (L 3), the number of eggs in feces and adult worm recovery rates from the small intestine of cotton rats were Cited by: 2. Roderick H.J. Houwen, in Wilson Disease, Mechanism. Zinc induces a negative copper balance, whose effect was already described by Schouwink , and confirmed subsequently in larger studies [5, 6].The negative copper balance under zinc therapy is a consequence of suppression of intestinal copper uptake, as can be visualized by 64 Cu .It is directly related to increased metallothionein.
Respiratory viral infection is a great human health concern, resulting in disease, death and economic losses. Cotton rats (Sigmodon hispidus) have been particularly useful in the study of the. It is known that copper (Cu) is highly accumulated in several organs in the perinatal period, suggesting changes in Cu metabolism with development, although the precise mechanisms are still unclear.
To elucidate the mechanisms underlying Cu accumulation in the organs of neonatal rats. COPPER AND LIPID METABOLISM IN CATTLE Ward and Spears () were the first to report that supplemental Cu decreased 12th-rib subcutaneous adi-pose tissue depth in steers.
In this experiment, Angus Copper and lipid metabolism in beef cattle: A review1,2 T. Engle3 Department of Animal Sciences, Colorado State University, Fort Collins An attempt was made to unravel further the mechanism by which high dietary concentrations of ascorbic acid influence copper metabolism.
The addition of ascorbic acid to the diet of rats caused about a twofold increase in plasma ascorbate concentrations and reduced group mean plasma and tissue concentrations of Cu. Copper toxicity has been implicated in various neurodegenerative disorders such as Wilson's disease and Alzheimer's disease.
Free copper in the brain is toxic and leads to neuronal and cellular damage, through free radical generation. Melatonin has been investigated as a possible copper ion chelator.
Melatonin could prevent copper-induced neuronal and cellular damage through binding with. The cotton rat (Sigmodon hispidus) is a New World rodent species that has a long-standing history as an experimental animal model due to its unique susceptibility to human viruses.
Furthermore, wild cotton rats are associated with a large variety of known or potentially zoonotic pathogens. The transport and cellular metabolism of Cu depends on a series of membrane proteins and smaller soluble peptides that comprise a functionally integrated system for maintaining cellular Cu homeostasis.
Inward transport across the plasma membrane appears to be a function of integral membrane proteins that form the channels that select Cu ions for passage. Two membrane-bound Cu-transporting. We report the identification and characterization of CTR1, a gene in the yeast S.
cerevisiae that encodes a multispanning plasma membrane protein specifically required for high affinity copper transport into the cell.
The predicted protein contains a methionine- and serine-rich domain that includes 11 examples of the sequence Met-X2-Met, a motif noted in proteins involved in bacterial copper. Abstract. Hispid cotton rats (Sigmodon hispidus) ingest both monocotyledon (monocot) and dicotyledon (dicot) plants, ostensibly to balance intake of the Texas coastal prairie, monocots are more abundant, require less handling time, and have more fiber and soluble carbohydrates than dicots, which contain more protein, lipid, water, energy, and minerals.
Adult rats were given by vein 64Cu, with mg stable Cu as copper acetate, and were killed at intervals from 3 min to 7 days after the injection. Initially, 64Cu in plasma was in direct-reacting form but it entered coeruloplasmin to the extent of 10, 50 and 98% of plasma 64Cu after 1, 6 and 39 h, respectively; activity disappeared from plasma at 2% per h after 2 days.
The Cu concentration was about 40 times higher in the liver of LEC (Long-Evans with a cinnamon-like coat color) rats aged 77 days (± μg/g liver) than in Fischer rats (± μg/g liver). However, in the kidney and brain of the LEC rats, Cu concentrations were lower than in these organs of the Fischer rats.
Cu concentration in the hepatic metallothionein fraction was about Copper Metabolism Gandham. Rajeev 2. • Total body copper is about mg. • It is present in all tissues. • The highest concentrations are found in liver, kidney, with significant amount in cardiac and skeletal muscle & in bone.
• Sources: • Shellfish, liver, kidneys, egg yolk & some legumes are rich in copper. Factors influencing the plasma copper level of the albino rat.
Am J Physiol. Dec; (3)– LAHEY ME, GUBLER CJ, CARTWRIGHT GE, WINTROBE MM. Studies on copper metabolism. VII. Blood copper in pregnancy and various pathologic states. J Clin Invest. Apr; 32 (4)– [PMC free article] Rath CE, Finch CA. CHEMICAL. Competition studies between iron and copper uptake by Caco-2 cells.
(A) Caco-2 cells were grown in bicameral inserts and incubated from the apical side with 5 lM 64 Cu–histidine with or without. The aim of this study was to investigate the copper metabolism during transition from the ETCM (up to days-old) to the ATCM in the rats.
It was shown that in the liver, copper was accumulated in the nuclei during the first 5 days of life, and then it was re-located to the mitochondria.Many metals have biological functions and play important roles in human health.
Copper (Cu) is an essential metal that supports normal cellular physiology. Significant research efforts have focused on identifying the molecules and pathways involved in dietary Cu uptake in the digestive tract. The lack of an adequate in vitro model for assessing Cu transport processes in the gut has led to.Recent studies, mostly performed in the yeast Saccharomyces cerevisiae, have provided new clues about 1) the source of the copper used for COX metallation; 2) the roles of Sco1p and Cox11p, the proteins involved in the direct delivery of copper to the Cu A and Cu B sites, respectively; 3) the action mechanism of Cox17p, a copper chaperone that.